M icropinocytosis of Transferrin by Developing
نویسندگان
چکیده
Electron-microscopic examination of rat or ferritin conjugated to nonspecific rabbit reticulocytes and normoblasts incubated lgG. These observations support the conwith transferrin conjugated to ferritin or cept that transferrin binds to a surface ferritin-labeled antitransferrin revealed membrane receptor and is subsequently binding of ferritin conjugates to the surinternalized by the developing red cell. face membrane, and uptake of ferritin Time course and temperature dependence conjugates in micropinocytotic vesicles. No studies suggest the endocytosis of transbinding or endocytosis of ferritin was ferrin may be an important mechanism in visualized when rat reticulocytes or normodelivery of iron to the developing red cell. blasts were incubated with ferritin alone
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